• Tailor-made HIV treatment closer to reality

    Updated: 2009-11-30 09:54:33
    Story Summary: Tailor-made HIV treatment closer to realityA new type of stem cells found in prostate may be involved in cancer– 9 Sep 2009 — A new type of stem cell found in the prostate of adult mice can be a source of prostate cancer, according to a new study. This is a vaccine made [...] Related posts:Tailor-made HIV/AIDS treatment closer to realityTailor-Made HIV/AIDS Treatment Closer To RealityLaser-Controlled Humans Closer to Reality | Wired Science

  • A Cancer-Fighting Implant

    Updated: 2009-11-30 09:53:13
    Story Summary: Unlike traditional vaccines, therapeutic cancer vaccines are designed to halt or reverse the course of the disease after it has developed. While cancer vaccines come in several variations, the general approach is to trigger the immune system to recognize and destroy cells bearing a cancer-specific marker. The immune system can be tuned to [...] Related posts:New Hope for Neuron ProtectionCancer-causing Protein Can Also Help Fight The Tumors It CausesDelivery Of Cancer-Fighting Molecules Improved By U-Iowa

  • The AIDS Institute, Nobel Prize Winner Join on World AIDS Day to Call for More Therapeutic Vaccine Funding

    Updated: 2009-11-30 06:17:13
    Story Summary: }{Interviews with researchers pursuing therapeutic vaccines can be arranged through contacts. }Newswise — In honor of World AIDS Day, The AIDS Institute (TAI), one of the nations leading advocacy organizations for support of people with HIV/AIDS and their providers, joined Nobel Laureate Dr. Francoise Barre-Sinoussi, in calling for government leaders, patient advocates [...] Related posts:SAfrica stops funding for AIDS vaccine researchAIDS vaccine funding down 10% in 2008Formatech, Inc. to Donate Services to Formulate and Fill GeoVax Labs, Inc. HIV/AIDS Vaccine under Its aFillanthropyaC/ Programa

  • Knockouts in Human Cells Point to Pathogenic Targets

    Updated: 2009-11-30 02:41:13
    Story Summary: RELEVANCE: With the ability to generate knockout cells for most human genes, the authors were able to find genes used by pathogens to enter and kill human cells. The identification of such factors could aid the future development of new therapeutics to combat infectious disease. Now Carette and co-workers have used a similar [...] Related posts:Knockouts in human cells point to pathogenic targetsReprogramming human cells without inserting genesNews: Johns Hopkins researchers edit genes in human stem cells.

  • Largest Gene Study In Childhood IBD Finds 5 New Genes

    Updated: 2009-11-30 00:18:33
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags adult onset causative role genomics one grants hapmap Largest Gene Study In Childhood IBD Finds 5 New Genes Posted on 30 November 2009 00:18 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary Most gene analyses of IBD have focused on adult-onset disease , but the Center for Applied Genomics-one of the worlds largest pediatric genotyping programs-at Childrens Hospital has concentrated on childhood-onset IBD , which tends to be more severe than adult-onset disease . The study team identified five new gene regions that raise the risk of early-onset IBD , on chromosomes 16, 22, 10, 2 and 19. The most significant finding was at chromosome locus 16p11, which contains the IL27 gene that carries the code for a cytokine , or signaling protein , also called IL27. T helper 17 cells are recently discovered cells that lead to severe inflammation and tissue injury in autoimmune diseases . IBD is an autoimmune disease , in which a persons immune system runs out of control and attacks the body . There are many cytokines in our immune system , but our

  • Cells defend themselves from viruses, bacteria with armour of protein errors

    Updated: 2009-11-29 23:05:13
    Story Summary: These regulated errors comprise a novel non-genetic mechanism by which cells can rapidly make important proteins more resistant to attack when stressed, said Tao Pan, Professor of Biochemistry and Molecular Biology at the University of Chicago. A team of 18 scientists from the University of Chicago and the National Institute of Allergy and [...] Related posts:Cells defend themselves from viruses, bacteria with armor of protein errorsChemotherapy resistance: Checkpoint protein provides armour against cancer drugsResearchers Examine How Viruses Destroy Bacteria

  • The Only H1N1 Vaccine Available For Swine Produced And Shipped By Iowa State Researcher

    Updated: 2009-11-29 19:30:33
    Story Summary: We shipped about 20,000 with about another 11,000 doses to go out to them later. It isnt uncommon for vaccinations to be used in what we call the face of an outbreak, he said. Since these pigs got sick and had a confirmed diagnosis, I think more farmers are going to want to [...] Related posts:Iowa State University researcher develops vaccine for H1N1 flu virus in swine – insciencesState fund advances swine vaccine research, six other Iowa State projectsSwine protection – News – The Engineer

  • Sinovac Establishes Joint Venture to Expand Human-Use Vaccine Development and Manufacturing Capabilities

    Updated: 2009-11-29 16:29:19
    Story Summary: By leveraging the favorable investment environment, relatively low operating cost and its existing facilities, this JV enables Sinovac to cost effectively establish manufacturing platforms for live attenuated vaccines and vero cell cultured vaccines, thus adding another important manufacturing site for Sinovacs vaccine products. Sinovac Dalian will be headquartered in , and will occupy [...] Related posts:Sinovac Receives Purchase Order from Shanghai Government to Supply Hepatitis A Vaccine Healive(R)Sinovac Receives Chinas First Influenza A (H1N1) Vaccine OrderCadila Pharmaceuticals Launches Joint Venture With Novavax in India

  • Tripep: The ChronVac-CA(r) Study Has Been Successfully Completed with Good Safety and Favorable Clinical Data

    Updated: 2009-11-29 15:53:13
    : Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags booster dose hepatitis rapid loss research projects technology platform Tripep : The ChronVac-CA(r Study Has Been Successfully Completed with Good Safety and Favorable Clinical Data Posted on 29 November 2009 15:53 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary In the 500 ug dose group 2 3 patients showed transient reductions in serum levels of HCV RNA up to 1,5log10 and in the same two patients T cell responses to the vaccine lasting This provides a proof-of-concept for the therapeutic strategy and supports further clinical development . In addition , early data from three patients who now have initiated standard of care treatment after completing the clinical trial have experienced a rapid loss of the virus , possibly suggesting a role for ChronVac-C(r in combination therapies . This data will be monitored for as many patients as possible during the coming year to obtain a more solid data base . Tripep will therefore pursue clinical development of ChronVac-C(r along two lines , the current ChronVac-C(r as in as an addition to

  • Biological H1N1 Vaccines: Too Little, Too Late

    Updated: 2009-11-29 14:01:19
    Story Summary: The new data shows that the lethality of the H1N1 (Swine Flu) virus has dropped from its peak of 3. The new data shows changes in the Replikin Count*, a measure of a viruss ability to rapidly replicate. In April 2008, Replikins issued a warning of an impending H1N1 influenza epidemic when the [...] Related posts:Biological H1N1 Vaccines: Too Little, Too LateFirst H1N1 Swine Flu Vaccine, Replikins-Based, Is Ready Now for Testing WorldwideLatest Replikins Data Predicts Continued High Level of H1N1 (Swine Flu) Infectivity and Lethality

  • Will Vaccines Change The Face Of Cancer Treatment?

    Updated: 2009-11-29 09:54:33
    Story Summary: According to Kalorama, cancer vaccine sales will more than double from $1. This unprecedented growth is creating countless opportunities for market participants. These will lead to tailored treatments based on a tumors specific genetic profile, allowing physicians to treat tumors based on their genetic make-up rather than their location. Several promising vaccines are [...] Related posts:231 New Genes Associated With Head And Neck Cancer Revealed By StudyDNA Sequencing at Your Doctors Office? Not Impossible, Says ReportMore Targeted Cancer Treatment Likely Following Discovery In Worms

  • The Benefits of Anti-drug Antibodies

    Updated: 2009-11-29 09:05:19
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags amino acids capillary electrophoresis precipitation product development size exclusion The Benefits of Anti-drug Antibodies Posted on 29 November 2009 09:05 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary Factors causing immunogenicityThe factors that cause immunogenicity of these products could be patient-related , disease-related and product-related . Some patients with chronic infections may be more prone to an immune response against a therapeutic protein . Patients with autoimmune disease , with an altered immunological tolerance to self-proteins , may react differently . In some conditions such as malnutrition , advanced metastatic disease , organ failure , an immune response against a therapeutic protein might be less likely to occur due to an impaired immune system . Food and Drug Administration FDA in the USA has a policy to include immunogenicity as part of the review of clinical safety assessments for biologic license applications . However as of now , no comprehensive guidelines exist on the approaches that are required for

  • WHO Investigates Cases Of H1N1 Drug Resistance In U.S., Britain

    Updated: 2009-11-29 08:41:13
    Story Summary: In a second story, Reutersexamines a Chinese health officials recent warnings that the country be alert for the mixing of the H1N1 virus with the H5N1 (bird flu) virus, resulting in a more deadly virus. However, under the current timeline, the plant still needs to be licensed by the Food and Drug Administration [...] Related posts:Five more swine flu cases linked to Alleyns School as cases in Britain hit 39 – TelegraphAs Influenza Cases Rise In Europe, Experts Urge Uptake Of H1N1 VaccineH1N1 Cases Confirmed In Douglas, Morton Counties, Flu and Cold

  • Researchers identify proteins in lung cancer cells that may provide potential drug targets

    Updated: 2009-11-29 06:37:19
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags drugs lung cancer lung cancers martin steffen proteins Researchers identify proteins in lung cancer cells that may provide potential drug targets Posted on 29 November 2009 06:37 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary Signal transduction is in large part controlled by a process called phosphorylation . Drugs are most effective on cancers when they attack the proteins that are activated , he added . While cancers are highly heterogeous in their make-up , the BU researchers believe that a drug that would target this collection of proteins would be effective treatment for most lung cancers . This is the first statistically validated phosphopeptide signature to diagnose any disease , much less cancer or lung cancer , explained senior co-author Martin Steffen , MD , PhD , an assistant professor of pathology and laboratory medicine at BUSM , and director , Proteomics Core Facility at BUSM . Funding for this study was provided by the National Human Genome Research Institute and the American Lung Association . Most of what you read here

  • Exome-Sequencing Might Help Identify Genetic Cause Of Thousands Of Disorders

    Updated: 2009-11-29 05:06:33
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags fetuses grants methotrexate mouths pregnancy Exome-Sequencing Might Help Identify Genetic Cause Of Thousands Of Disorders Posted on 29 November 2009 05:06 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary The study , Exome sequencing identifies the cause of a mendelian disorder , was led by University of Washington UW researchers and published Nov . 13 in Nature Genetics . One of the reasons that this strategy is so powerful is that the scientists need only use a small number of unrelated cases to find the gene , said the other senior author of the study , Dr . Jay Shendure , UW assistant professor of genome sciences . People with this syndrome have a number of malformations affecting their mouths , eyelids , ears , and feet . Once we discover the causative gene , she added , we can begin to look at how the gene might lead to the development of disease and what factors predict the outcome . After scientists identify one causative gene and its repercussions , by extension they might discover other genes or environmental agents that affect

  • RNA network seen in live bacterial cells for first time

    Updated: 2009-11-29 00:18:33
    Story Summary: Now, a new technology has given scientists the first look ever at RNA in a live bacteria cell — a sight that could offer new information about how the molecule moves and works. Interest in RNA, which plays a key role in manufacturing proteins, has increased in recent years, due in large part [...] Related posts:Seeing RNA Network In Live Bacterial Cells For The First Time At Boston UniversityScientists first to see RNA network in live bacterial cellsBoston University scientists first to see RNA network in live bacterial cells

  • Common Genetic Contributions To Plasma Lipoprotein Profile Determined By Large Scale, Genome-wide Genetic Analysis

    Updated: 2009-11-29 00:17:13
    , Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags animals factual information genetic contributions miletich plasma Common Genetic Contributions To Plasma Lipoprotein Profile Determined By Large Scale , Genome-wide Genetic Analysis Posted on 29 November 2009 12:17 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary This large scale analysis of the effects of common genetic variation on plasma lipoprotein profile , a critical component of cardiovascular risk , identified 43 genetic loci contributing to lipoprotein metabolism , including 10 loci not previously recognized in other whole genome analyses . The findings are published on November 20 in the open-access journal PLoS Genetics . While the overall concentration of each of the major classes can be estimated by the clinical measures of LDL-cholesterol , HDL-cholesterol , and triglycerides , the determinations of the concentration of the sub-species by NMR methodology in the current study provide a more precise picture of lipoprotein profile . Analysis in the Framingham Heart Study was supported by the NHLBI HL54776 Other than Amgen ,

  • Experts scan disease links with Chinese gene map

    Updated: 2009-11-28 23:13:19
    Story Summary: The huge sample of 8,200 ethnic Chinese participants were drawn from 10 Chinese provinces and Singapore. Interestingly, the scientists also found genetic variants between different Chinese dialect groups. The team appears to have made some headway with two chronic autoimmune diseases – psoriasis and systemic lupus erythematosus (SLE). Psoriasis causes red scaly patches [...] Related posts:First genetic map of Han Chinese may aid search for disease susceptibility genesMoles And Melanoma: Genetic Links To Skin Cancer FoundOptimistic Prospect of Chinese A (H1N1) Influenza Vaccine Market

  • U.S. sees rise in secondary infections after flu

    Updated: 2009-11-28 20:45:19
    Story Summary: And while such infections normally affect people over 65, these were almost all among people under 60, she said. But only about a quarter of adults who should get it ever do, Schuchat said. Children are protected against seven strains of these bacteria with Pfizer Incs Prevnar. Strep infections can be treated with [...] Related posts:Swine flu vaccines delayed, CDC saysU.S. H1N1 vaccine output rising quickly: Sanofi CEOBill Clinton to attend AIDS charity gala in Cannes | Lifestyle | Reuters

  • Macomb County Health Department Schedules Two More H1N1 Flu Vaccine Clinics Dec. 3 and 5

    Updated: 2009-11-28 18:17:19
    . Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags department requests dose one flu vaccine steve gold vaccine clinics Macomb County Health Department Schedules Two More H1N1 Flu Vaccine Clinics Dec . 3 and 5 Posted on 28 November 2009 18:17 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary They are being offered at no charge and both take place at Freedom Hill County Park in Sterling Heights . The Dec . 3 clinic will be held from noon to 7 p . m . the Dec . 5 one will run from 9 a . m . to 3 p . m . The thimerosol-free version of the injectable vaccine will be available upon request , while supplies last . The health department requests that those whose children received dose one of the vaccine through one of its clinics please bring the card they were given that day with them , so their records can be updated appropriately . Call your doctor to see if he or she is offering the vaccine to patients in the office setting , said Steve Gold , Macomb County Health Department deputy health officer . Editors note : Through its first 11 clinics , not including Nov . 24ths , the Macomb County

  • Discovery Allows Scientists For The First Time To Annotate Genomes Experimentally

    Updated: 2009-11-28 18:17:13
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags biological processes biotechnology paper commodity chemicals drugs mid 1990s Discovery Allows Scientists For The First Time To Annotate Genomes Experimentally Posted on 28 November 2009 18:17 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary The information collected from genome sequencing will provide the raw data for the field of bioinformatics , where computer science and biology meet . Since the publication of the first full genome sequence in the mid-1990s , scientists have been working to identify the genomic location of all the gene products involved in the complex biological processes in a single organism . In a recent Nature Biotechnologypaper , the researchers describe a four-step systems approach that integrates multiple genome-scale measurements on the basis of genetic information flow to identify the organizational elements and map them onto the genome sequence . Palsson said there are many significant implications of this new finding , such as enhancing metabolic engineering such as the engineering of microorganisms to make

  • Skin grafts from stem cells

    Updated: 2009-11-28 15:49:19
    Story Summary: Where did the story come from?The research was carried out by Dr Hind Guenou and colleagues from the Institute for Stem Cell Therapy and Exploration of Monogenic disease, and BIOalternatives SAS in France along with colleagues in Madrid. BBC News has covered this research in a balanced way, pointing out that this was [...] Related posts:How stem cells make skinSkin-like tissue developed from human embryonic stem cellsSkin-like tissue developed from human embryonic stem cells

  • New stress-related gene modulates high blood pressure in mice and men

    Updated: 2009-11-28 14:41:13
    Story Summary: The German team, led by Lutz Hein M. D. , in collaboration with Monika Stoll, Ph. D. , generated mice lacking the phosducin gene and compared them with normal mice. The mice lacking this gene developed high blood pressure under various conditions of stress. The volunteers were then asked to perform certain standardized [...] Related posts:Genes Yield Clues to High Blood Pressure – MSN Health & Fitness – High Blood PressureNew Genes Implicated in High Blood Pressure- 5/10/09Anti-ageing gene linked to high blood pressure

  • Is dirt good for kids?

    Updated: 2009-11-28 13:21:19
    Story Summary: Where did the story come from?The study was carried out by Dr Yuping Lai and colleagues from the University of California and other academic institutions across the USA. This was laboratory research and included some studies in live mice in which injury was induced. The findings pave the way for future studies of [...] Related posts:Fighting Tuberculosis with Anti-Inflammatory Drugs Shown Possible in Animal Studies- 6/29/09News From The Journal Of Clinical Investigation: July 13, 2009How eczema might lead to asthma

  • Knockouts in human cells point to pathogenic targets

    Updated: 2009-11-28 11:05:13
    Story Summary: (November 26, 2009) Whitehead researchers have developed a new type of genetic screen for human cells to pinpoint specific genes and proteins used by pathogens, according to their paper in Science. In this rare cell line, Carette and co-workers generated mutations in almost all human genes and used this collection to screen [...] Related posts:Knockouts in Human Cells Point to Pathogenic TargetsSkin-like Tissue Developed from Human Embryonic Stem CellsSkin-like Tissue Developed From Human Embryonic Stem Cells

  • Arming the Immune System against H1N1

    Updated: 2009-11-28 10:53:19
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags food drinks immune cell immunity immunologist presence Arming the Immune System against H1N1 Posted on 28 November 2009 10:53 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary Then the Cel-Sci researchers take those segments and attach them to another small molecule–an immune-cell-binding ligand that guides the complex straight to the immune cells in charge of initiating and directing an immune reaction . Immature dendritic cells are prompted to mature by the presence of these invaders the mature dendritic cells then activate T cells , which in turn stimulate very specific immunity against the virus . Its like a live virus vaccine–and more effective–but without the live virus , says Kenneth Rosenthal , an immunologist at Northeastern Ohio Universities Colleges of Medicine and Pharmacy who has collaborated with the Cel-Sci team . So far , the company has tested the LEAPS system in mice with herpes and arthritis , and found the approach to be successful in modulating the rodents immune responses . Avoid Swine Flu While DietingI dont believe

  • First-ever blueprint of a minimal cell is more complex than expected

    Updated: 2009-11-28 07:29:13
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags cellular machinery microsoft proteome surprise transcriptome First-ever blueprint of a minimal cell is more complex than expected Posted on 28 November 2009 07:29 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary It is also one of the smallest prokaryotes organisms whose cells have no nucleus that dont depend on a hosts cellular machinery to reproduce . One team of scientists described M . pneumoniaes transcriptome , identifying all the RNA molecules , or transcripts , produced from its DNA , under various environmental conditions . Another defined all the metabolic reactions that occurred in it , collectively known as its metabolome , under the same conditions . A third team identified every multi-protein complex the bacterium produced , thus characterising its proteome organisation . Remarkably , the regulation of this bacteriums transcriptome is much more similar to that of eukaryotes organisms whose cells have a nucleus than previously thought . And although its genes are arranged in groups as is typical of bacteria , M .

  • Heparanase-specific shRNA: A novel therapeutic strategy in human gastric cancer

    Updated: 2009-11-28 05:57:19
    Story Summary: com86-105-908-0039Previous studies have indicated that the heparanase (HPA) is correlated with histopathological parameters and poor prognosis of gastric cancers. Although their efficiencies in inhibiting the expression of HPA, the traditional HPA inhibitors may produce nonspecific and undesirable effects. Results showed that stable transfection of HPA-specific shRNA, but not of scrambled shRNA and mock [...] Related posts:Heparanase-specific shRNA: A novel therapeutic strategy in human gastric cancerAlpha-fetoprotein can affect the development of rat colons?Adenoviral vector specifically targeted to EphA2 receptor in pancreatic cancer cells

  • Why Some Vaccines May Require a Booster

    Updated: 2009-11-28 05:42:27
    Story Summary: The problem is that this scenario is not true for all diseases. Other examples of vaccines that do not appear to require boosters because the pace of disease progression is slow include: polio, measles, mumps, and German measles. Dr. Pichichero StudyThe study found, however, that there are several newer vaccines that may [...] Related posts:The News Record – Incoming students may require vaccineStudy Examines Mercury in VaccinesSupply of Key Childrens Vaccine Almost Back to Normal – Forbes.com

  • Biological H1N1 Vaccines: Too Little, Too Late

    Updated: 2009-11-28 03:53:13
    Story Summary: The new data shows that the lethality of the H1N1 (Swine Flu) virus has dropped from its peak of 3. The new data shows changes in the Replikin Count*, a measure of a viruss ability to rapidly replicate. In April 2008, Replikins issued a warning of an impending H1N1 influenza epidemic when the [...] Related posts:Biological H1N1 Vaccines: Too Little, Too LateFirst H1N1 Swine Flu Vaccine, Replikins-Based, Is Ready Now for Testing WorldwideLatest Replikins Data Predicts Continued High Level of H1N1 (Swine Flu) Infectivity and Lethality

  • Researchers discover biological basis of bacterial immune system

    Updated: 2009-11-28 03:29:19
    Story Summary: Understanding how bacteria defend themselves gives us important information that can be used to weaken bacteria that are harmful and strengthen bacteria that are helpful, said Michael Terns, a professor of biochemistry and molecular biology in UGAs Franklin College of Arts and Sciences. You can look at one as a police dog that [...] Related posts:Researchers discover biological basis of bacterial immune systemResearchers discover RNA repair system in bacteriaJ. Craig Venter Institute Researchers Clone and Engineer Bacterial Genomes in Yeast and Transplant Genomes Back Into Bacterial Cells

  • First genetic map of Han Chinese may aid search for disease susceptibility genes

    Updated: 2009-11-28 01:01:19
    Story Summary: was published online today by the American Journal of Human Geneticsby scientists at the Genome Institute of Singapore (GIS). Based on genome-wide DNA variation information in over 6,000 Han Chinese samples from 10 provinces in China, this new map provides information about the population structure and evolutionary history of this group of people [...] Related posts:Experts scan disease links with Chinese gene mapOptimistic Prospect of Chinese A (H1N1) Influenza Vaccine MarketGeography and History Shape Genetic Differences in Humans

  • Cells defend themselves from viruses, bacteria with armor of protein errors

    Updated: 2009-11-28 00:17:13
    , Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags genetic mechanism oxidation proteins stress trna Cells defend themselves from viruses , bacteria with armor of protein errors Posted on 28 November 2009 00:17 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary Cells defend themselves from viruses , bacteria with armor of protein errorsWhen cells are confronted with an invading virus or bacteria or exposed to an irritating chemical , they protect themselves by going off their DNA recipe and inserting the wrong amino acid into new proteins to defend them against damage , scientists have discovered . These regulated errors comprise a novel non-genetic mechanism by which cells can rapidly make important proteins more resistant to attack when stressed , said Tao Pan , Professor of Biochemistry and Molecular Biology at the University of Chicago . A team of 18 scientists from the University of Chicago and the National Institute of Allergy and Infectious Disease led by Pan and Jonathan Yewdell published the findings Thursday in the journal Nature . Transfer RNAs tRNA one for each of the 20 amino

  • Researchers at Signature Genomics Attribute Diverse Spectrum of Neurological Problems to Chromosome Abnormalities of Genetic Region Associated with Autism

    Updated: 2009-11-27 23:28:27
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags chromosome abnormalities deletions genomics populations product development Researchers at Signature Genomics Attribute Diverse Spectrum of Neurological Problems to Chromosome Abnormalities of Genetic Region Associated with Autism Posted on 27 November 2009 23:28 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary Recent searches for genetic aberrations in large populations of individuals with autism or an autism spectrum disorder ASD have identified missing or extra copies of a small portion of DNA on chromosome 16 in a few of these individuals . A majority of individuals with the duplication had delayed development and or specific deficits in speech or language , although these features were not as consistent as seen with the deletions of the same region . This allowed us to show that abnormalities of this region are not unique to autism but likely play a role in more general neurodevelopmental problems,a said Dr . Blake C . Ballif , Ph . D . Director of Product Development and Research at Signature and senior author of the study . aThese

  • Tailor-made HIV/AIDS treatment closer to reality

    Updated: 2009-11-27 22:33:19
    Story Summary: The new approach is an immunotherapy customized for each individual patient, and was developed by Dr. J-P. Routy from the Research Institute of the MUHC in collaboration with Dr. R. Sekaly from the Universite de Montreal. The new therapy uses dendritic cells which are removed from each HIV-infected patient and [...] Related posts:Tailor-Made HIV/AIDS Treatment Closer To RealityTailor-made HIV treatment closer to realityHeparanase-specific shRNA: A novel therapeutic strategy in human gastric cancer

  • SinoFresh Nasal Spray Achieves Positive Results Against H1N1 (Swine Flu) Virus in Initial Pilot Animal Study

    Updated: 2009-11-27 20:21:27
    Story Summary: (PINKSHEETS: SFSH) announced today the successful results of its initial pilot animal study testing the efficacy of the SinoFresh Nasal Spray product when used on animals infected with the H1N1 (swine flu) virus. The study data suggests that treatment with SinoFresh allowed the infected animals to recover more rapidly from H1N1 infection than [...] Related posts:Universal vaccine in nasal spray | smh.com.auNOVAVAX Virus-Like Particle Vaccine Protects Against 2009 Pandemic H1N1 Influenza VirusAethlon Medical Releases Medical Device Data Against The H1N1 Swine Flu Virus

  • Researchers discover biological basis of bacterial immune system

    Updated: 2009-11-27 17:37:19
    Story Summary: In addition to mammalian immune systems that besiege the bugs, they have natural enemies called bacteriophages, viruses that kill half the bacteria on Earth every two days. Still, bacteria and another class of microorganisms called archaea (first discovered in extreme environments such as deep-sea volcanic vents) manage just fine, thank you, in part [...] Related posts:Researchers discover biological basis of bacterial immune systemSeeing RNA Network In Live Bacterial Cells For The First Time At Boston UniversityMessenger RNA with FLASH

  • NVHR: New Data Finding Fewer than 1 in 5 Hepatitis C Patients Receiving Antiviral Therapy is Wake-Up Call for Washington

    Updated: 2009-11-27 16:41:33
    : Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags antiviral therapy congressional action disproportionate share hepatitis c virus liver failure NVHR : New Data Finding Fewer than 1 in 5 Hepatitis C Patients Receiving Antiviral Therapy is Wake-Up Call for Washington Posted on 27 November 2009 16:41 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary The NVHR warns that without congressional action , millions of Americans infected with chronic hepatitis C virus particularly African Americans are at serious risk of developing cirrhosis , liver cancer , and liver failure and will add billions of dollars in unnecessary costs to our health care system every year . The NVHR is a coalition of more than 150 public , private , and voluntary organizations dedicated to reducing the incidence of infection , morbidity , and mortality from viral hepatitis in through strategic planning , leadership , coordination , advocacy , and research . Without action from to support state-based efforts , millions of Americans will suffer from severe hepatitis-related complications and cost our health system tens of

  • Gene increases effectiveness of drugs used to fight cancer and allows reduction in dosage

    Updated: 2009-11-27 14:07:27
    Story Summary: es34-958-243-534This image shows the effect of gene therapy combined with cytotoxic agents in E spheroids derived from breast cancer cell line MCF-7. So far, attempts to use many chemotherapeutic (cytotoxic) agents similar to the E gene have shown severe limitations resulting from their toxicity and their poor affinity with the tumour. Her work [...] Related posts:Gene increases effectiveness of drugs used to fight cancer and allows reduction in dosageMoving Gene Therapy Forward With Mobile DNAMDRNA To Present Data On Tumor Reduction At Cancer Therapy Conference

  • Plasma levels of GGT and ALB and their genetic correlations with cardiovascular risk factors

    Updated: 2009-11-27 11:00:27
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags chromosomal regions liver mild dehydration pathogenesis proteins Plasma levels of GGT and ALB and their genetic correlations with cardiovascular risk factors Posted on 27 November 2009 11:00 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary Plasma levels of GGT and ALB and their genetic correlations with cardiovascular risk factorsNovember 24, 2009 Two indicators of liver function , Gamma-glutamyl transferase GGT and albumin ALB have been implicated in the pathogenesis of atherosclerosis . It is known that the variation in the plasma level of these liver related proteins is genetically influenced . The purpose of this study published in the December 2009 issue of Experimental Biology and Medicinewas to identify chromosomal regions containing genes that affect the variation in the plasma levels of GGT and albumin and to determine whether genes contributing to variation in these hepatic proteins also influence variation in known cardiovascular diseaserisk factors . Additionally , if a common set of genes are found to regulate variation in

  • Prodesses ProParaflu+(TM) Assay Cleared for US Marketing by FDA

    Updated: 2009-11-27 07:53:27
    Story Summary: Prodesse markets these respiratory tests in the United States:ProFlu+(TM), which received FDA clearance in 2008 to detect and differentiate influenza A virus, influenza B virus, and respiratory syncytial virus (RSV). The real-time RT-PCR technology used in Prodesses assays is simple to use and easily integrates into a labs existing workflow. All products have [...] Related posts:Qiagen test kits can detect swine-flu virus: News from QiagenProdesse files to market flu diagnostic tool (WTN News)A Highly Reproducible Cell Migration Screening Assay

  • Vaccine quest boosted by HIV that infects monkeys

    Updated: 2009-11-27 07:05:33
    Story Summary: All that could change if the new animal model of HIV is successful. She presented her teams results at an AIDS research meetingin Boston last month. But HIV doesnt cause disease in chimps and their endangered status limited researchers use of them. Today, labs use two main varieties of SIV: one from sooty [...] Related posts:Engineered antibodies fight AIDS virus in monkeysT-Cell Vaccine Reduces Simian Immunodeficiency Virus Levels In Semen Of Monkeys During Primary InfectionVaccine Shields Monkeys From Simian Form of HIV – MSN Health & Fitness – AIDS/HIV

  • Yale Researchers Target Tick Saliva In Their Search For Lyme Disease

    Updated: 2009-11-27 05:17:19
    Story Summary: When combined with outer surface proteins of B. burgdorferi, the protection was even greater. Several years ago there was a Lyme vaccine on the market that utilized just the outer surface proteins of the bacteria. It was taken off the market in 2002, and to date no other antigen has been tested [...] Related posts:Tick Saliva: New Target for Lyme Disease VaccineNew Piece In Alzheimers Puzzle Discovered By Yale ResearchersNew Piece In Alzheimers Puzzle Discovered By Yale Researchers

  • Sky Foundation, Inc. Raises More Than (Dollor) 100,000 to Find a Test for Early Detection of Pancreatic Cancer

    Updated: 2009-11-27 04:46:27
    Story Summary: The Sky Foundation Pancreatic Cancer Research Project is a partnership between the Karmanos Cancer Institute and Henry Ford Health System. D. , is leading the research projects efforts to identify pancreatic cancer biomarkers. Dr. Tainsky believes that a diagnostic test for the early detection of pancreatic cancer can be found within three [...] Related posts:New tool may help with early detection of deadly pancreatic cancerBlood Test May Spot Pancreatic Cancer EarlyCompendium of Pancreatic Cancer Biomarkers Established as Strategic Approach to Early-Detection Research- 4/6/09

  • As Influenza Cases Rise In Europe, Experts Urge Uptake Of H1N1 Vaccine

    Updated: 2009-11-27 02:49:19
    , Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags influenza vaccines influenza viruses medical information medical intervention spain As Influenza Cases Rise In Europe , Experts Urge Uptake Of H1N1 Vaccine Posted on 27 November 2009 02:49 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary Influenza is reported by the World Health Organization as widespread in 10 European countries Belgium , Iceland , Ireland , Italy , Netherlands , Norway , Russia , Spain , Sweden and the UK with cases of respiratory illness requiring medical intervention increasing in 17 countries in Italy , for example , the number of cases per week doubled recently . Not only are levels of influenza unusually high for this time of year , the H1N1virus accounts for 99 percent of cases . Physicians should do their best to advertise vaccination among their patients , with special reference to the most vulnerable ones . Some have argued that since the seasonal influenza vaccine was intended for elderly , most of the data available are from adults rather than children . However , data have been acquired from more than 3000

  • Saving the single cysteine: New antioxidant system found

    Updated: 2009-11-27 02:17:33
    Story Summary: Now, researchers at the University of Michigan, along with colleagues in Belgium, have discovered a new antioxidant system that protects single cysteines. Over time, the injuries can lead to cancer, heart disease, Alzheimers disease and other serious medical conditions. To guard against such harm, our cells have special proteins that can repair or [...] Related posts:Single-stranded DNA-binding protein is dynamic, critical to DNA repairInterview: The life-saving shotPenn Study Finds That Antioxidant Found In Vegetables Has Implications For Treating Cystic Fibrosis

  • Deadly African Virus Threatens British Pig Industry

    Updated: 2009-11-27 01:39:27
    Story Summary: There is no cure or vaccine for the highly contagious virus that kills nearly all pigs that catch it. Scientists at the BBSRCs Institute for Animal Health (IAH), and the UNs Food and Agriculture Organisation (FAO) say that the threat should be taken seriously. says Dr Linda Dixon, Head of the ASF research [...] Related posts:Deadly new flu virus in US and Mexico may go pandemicDeadly new flu virus in US and Mexico may go pandemicGenetic analysis of swine flu virus reveals diverse parts

  • Opposites attract: Monkeys choose mating partners with different genes

    Updated: 2009-11-27 00:41:19
    Story Summary: The results obtained from mandrills, a species closely related to humans, support the disputed theory that humans are attracted to those with a dissimilar genetic make up to maintain genetic diversity. Female mandrills are more likely to reproduce with males whose genes are complementary, possibly because they smell out suitable candidates, according to [...] Related posts:Gene research finds opposites do attract | Science | The GuardianOpposites attract in human search for mate | ReutersResearchers discover mechanism that prevents two species from reproducing

  • JohnsonDiversey Launches Comprehensive Web Site Dedicated To H1N1 And Other Infectious Disease Prevention Information

    Updated: 2009-11-27 00:21:19
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags commercial spaces infection risk infectious disease information sources linkage JohnsonDiversey Launches Comprehensive Web Site Dedicated To H1N1 And Other Infectious Disease Prevention Information Posted on 27 November 2009 00:21 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary com , a one-stop resource for managing infection risk in schools , health settings and other commercial spaces . The site will also host topic-specific , expert videos to demonstrate the essential elements of infection control . The site is developed in English , but also provide linkage to JohnsonDiverseys infection control information in 14 languages . Additionally , JohnsonDiverseys infection control team will regularly post the most up-to-date public health information from the Centers for Disease Control and Infection CDC Department of Health and Human Services HHS and the World Health Organization WHO com is a 24 7 resource for people seeking the latest facts regarding infection control , said Dr . Ramirez , Vice President of Global Research and Development .

  • Alzheimers: Destructive amyloid-beta protein may also be essential for normal brain function

    Updated: 2009-11-26 21:53:19
    Story Summary: A reset button for drug researchersWithout amyloid-beta, a normal product of cellular metabolism, ones ability to learn and remember could be profoundly damaged, so drugs currently in development to eliminate amyloid-beta could be rendered obsolete. Her students Efrat Abramov and Iftach Dolev found that if this precise balance is even slightly disturbed, the [...] Related posts:Amyloid Beta Protein Gets Bum RapDietary composition modulates brain mass and amyloid beta levels in a mouse model of aggressive Alzheimers amyloid pathologyNews: Novel role of protein in generating amyloid-beta peptide.

  • UAB researchers discover antibody receptor identity, propose renaming immune-system gene

    Updated: 2009-11-26 21:29:33
    Story Summary: Study reveals new genetic culprit in deadly skin cancer– 30 Aug 2009 — Drawing on the power of DNA sequencing, National Institutes of Health researchers have identified a new group of genetic. New technique could eliminate inherited mitochondrial disease– 26 Aug 2009 — Researchers have developed an experimental technique with the potential to [...] Related posts:Researchers Discover Antibody Receptor Identity, Propose Renaming Immune-System GeneGene Found in Sudden Sleep Disorder Implicates the Immune SystemScientists discover gene mutation responsible for hereditary neuroendocrine tumor

  • Control Of Blood Clotting By Platelets Described; Provides Medical Promise

    Updated: 2009-11-26 19:25:27
    Story Summary: When a platelet is stimulated, such as by thrombin, the protein Disabled-2 (Dab2) moves from where it is stored inside of the platelet to the surface, where it interacts with the integrin receptor. That is, sulfatides partition Dab2 into two pools – one pool that is part of the clotting process and one [...] Related posts:Light-activated Lock Can Control Blood Clotting, Drug DeliveryMedical News: ASH: Common Genes Contribute to Blood Pressure Regulation – in Meeting Coverage, ASH: Hypertension from MedPage TodayMicroRNAs Hold Promise For Treating Diseases In Blood Vessels

  • Alzheimers research sheds light on potential treatments for urinary tract infections

    Updated: 2009-11-26 19:25:19
    Story Summary: D. , the Helen L. Stoever Professor of Molecular Microbiology at Washington University. Scientists in Hultgrens laboratory have worked for decades to understand the links between biofilms and UTIs. 6 billion in medical expenses every year in the United States, says co-lead author Jerome S. Pinkner, laboratory manager for Hultgren. D. [...] Related posts:Vaccine to prevent urinary tract infections shows early promisePromising Results From A Vaccine To Prevent Urinary Tract InfectionsNIH funds work at WPI on regenerating heart tissue and preventing urinary tract infections

  • New research shows versatility of amniotic fluid stem cells

    Updated: 2009-11-26 16:41:33
    Story Summary: Atalas team is currently evaluating the cells for their potential to treat diabetes and kidney disease. For the study, scientists generated two additional lines of stem cells from amniotic fluid using the same protocol developed by Atalas lab. They then investigated the incidence of EB formation in all three lines. Performing many independent [...] Related posts:Blood protein may hold key to stopping tumor growth in cancer patientsElbein Named Endocrinology Section Chief, Brings Diabetes Research Team to Wake Forest Baptist2 lines account for most human embryonic stem cell research, Stanford scholar finds

  • Flu Tips 2009

    Updated: 2009-11-26 16:18:27
    Story Summary: Does the H1N1 outbreak mean you have to skip the ham this holiday season?With H1N1 or swine flu continuing to make headlines in the media, many people who traditionally feast on ham are wondering whether its necessary to skip pork and go all-turkey or even vegetarian this holiday season. Cooking pork to an [...] Related posts:Sanofi Pasteur Begins Shipments Of Fluzone(R), Influenza Virus Vaccine For 2009 – 2010 Seasonal InfluenzaNIAID scientists study past flu pandemics for clues to future course of 2009 H1N1 virusFDA Approves Four Vaccines for 2009 H1N1 Influenza Virus

  • Gene Silencing To Boost Biological Drug Yields

    Updated: 2009-11-26 10:04:27
    Story Summary: Biological drugs, also called biologics, including protein-based drugs, monoclonal antibodies and vaccines, are made in bio-reactors containing cultured lines of living cells. Alnylam Pharmaceuticals of Cambridge, Massachusetts is setting up a new venture called Alnylam Biotherapeutics to develop RNAi technology and partner with drug companies to improve the cell cultures they use for [...] Related posts:Oral RNAi Drug Stops Inflammation in Mice, RXi Says | XconomyIDT secures funding for new gene silencing researchAlnylam, Cubist Gene-Blocking Drug Safe in Lung Test (Update1) – Bloomberg.com

  • Gene mismatch influences success of bone marrow transplants

    Updated: 2009-11-26 09:03:57
    Story Summary: When the gene, called UGT2B17, is missing from the donors genome but present in the recipients, transplants have a significantly greater risk of a serious side-effect known as graft-versus-host disease, in which immune cells from the donor attack tissues in the recipient. This finding gives us a glimpse into the genetic incompatibilities that [...] Related posts:Van Andel Institute researchers find gene that could lead to new therapies for bone marrow diseaseHematopoietic Stem Cell Treatment With A New Gene Therapy Vector: A First Success Treating A Brain DiseaseGene therapy to aid lung transplants

  • RXi Pharmaceuticals Wins 2009 RNAi Technology Innovation of the Year Award from Frost & Sullivan

    Updated: 2009-11-26 07:05:33
    Home About Archives Science Bookstore Terms of Service Privacy Policy Contact Us ADVERTISMENT ADVERTISMENT Tags biopharmaceutical company design delivery prestigious award rna interference todays news RXi Pharmaceuticals Wins 2009 RNAi Technology Innovation of the Year Award from Frost Sullivan Posted on 26 November 2009 07:05 by Alfie VN:F 1.6.9_936 please wait . Rating : 0.0 5 0 votes cast Story : Summary RXi Pharmaceuticals Wins 2009 RNAi Technology Innovation of the Year Award from Frost SullivanWORCESTER , Mass . BUSINESS WIRE RXi Pharmaceuticals Corporation Nasdaq : RXII a biopharmaceutical company pursuing the development and commercialization of proprietary therapeutics based on RNA interference RNAi today reported that the Company has received Frost Sullivans 2009 North American RNAi Therapeutic Design Delivery Technology Innovation of the Year Award for the development of its proprietary RNAi compounds , rxRNA , and advanced delivery approaches . The rxRNA compounds are designed specifically for therapeutic use and contain many of the properties needed to develop RNAi-based drugs . Commenting on todays news , Noah D . Beerman , President and Chief Executive Officer of RXi

  • HPA Statement On Possible Transmission

    Updated: 2009-11-26 06:57:27
    Story Summary: Further follow-up of cases and their close contacts both on the ward and in the community is underway to ascertain if there is evidence of onward transmission. The current cases of oseltamivir resistance under investigation have all occurred in patients with haematological problems which result in immuno-suppression either because of the disorder or [...] Related posts:Experts Keep Wary Eye on Tamiflu-Resistant Swine Flu200904284555 | Update: Drug Susceptibility of Swine-Origin Influenza A (H1N1) Viruses, April 2009 | / | Homeland SecurityStudy: New treatment may combat drug-resistant flu

  • Discovery By Biologists Of Bacterial Defense Mechanism Against Aggressive Oxygen

    Updated: 2009-11-26 03:50:27
    Story Summary: Proteins are extremely sensitive to oxidationProteins are the most important components of our bodys cells. This is certainly the case for proteins that contain sulfurous components, with the amino acid cysteine as the basis. This is why the cysteine building blocks often occur as pairs, in which the bond between the two sulfur [...] Related posts:Biologists discover bacterial defence mechanism against aggressive oxygenDismantling The Powerhouses In CellsNewswise Science News | Researchers Link Oxidation of Potassium Channel in Cells to Loss of Sensory Function in Aging

  • Cancer metabolism discovery uncovers new role of IDH1 gene mutation in brain cancer

    Updated: 2009-11-26 02:17:33
    Story Summary: This groundbreaking work is profound for the field, said Professor Lew Cantley, Ph. Additionally, there is an easily measured metabolic biomarker, 2HG, that will help in the diagnosis and treatment of any related therapeutics that arise from this work. Agios scientists uncovered the function of the IDH1 mutation by employing novel techniques in [...] Related posts:Two Gene Mutations Linked to Most Common Brain Cancers – 2/19/09Two Gene Mutations Linked to Most Common Brain Cancers – 2/19/09Skin Cancer Study Uncovers New Tumor Suppressor Gene

  • Major Pathologies Associated With Alzheimers Disease Reduced In Mice With Novel Gene

    Updated: 2009-11-26 00:43:27
    Story Summary: Additionally, the researchers demonstrated that RPS23R1 also exerts its function in human cells, suggesting that RPS23R1 signaling pathways are active in humans. While it is not yet known whether there are functional analogs of RPS23R1 in humans, further elucidation of RPS23R1 functions and mechanism of action may prove to be important for developing [...] Related posts:Novel Mouse Gene Suppresses Alzheimers Plaques And TanglesMouse gene suppresses Alzheimers plaques and tanglesNew insights into limb formation

  • Cannibalism clue to brain disease

    Updated: 2009-11-25 21:03:57
    Story Summary: A genetic study of the Fore tribe of Papua New Guinea has shown that certain members carry genetic mutations that protect them from a disease called kuru, which can be contracted by eating prion proteins in brain matter. The disease, which kills tribe members lacking the mutation, is similar to Creutzfeldt-Jakob disease (CJD), [...] Related posts:Pesticides blamed for some childhood brain cancers. — Environmental Health NewsSelected Update: Neurodegenerative disease: Proving the linkHow Prion Protein Damages Brain Cells, Brain & Nervous System

  • Discovery leads to effective treatment of painful skin condition

    Updated: 2009-11-25 18:29:27
    Story Summary: The study, published online November 24 in Molecular Therapydescribes a new treatment for pachyonychia congenita, an ultra-rare genetic skin condition caused by mutations in a gene called keratin. The disorder is characterized by painful, blistering calluses on the feet and limbs that limit a patients ability to walk. The result is exceptionally promising [...] Related posts:Genetic Testing Guidelines For Melanoma Are DevelopedPainful nerve condition may be improved by blocking protein – NewsGenetic Variation Discovery Could Improve Hepatitis C Treatment

  • Slimming gene discovered that regulates body fat

    Updated: 2009-11-25 16:41:33
    Story Summary: Larvae in which this gene is defective lose their entire fat reserves. Therefore the researchers called the gene schlank (German for slim). With the fruit fly Drosophila there is a rather paradox convention. Together with Dr. Reinhard Bauer and other employees the development biologist has explored what exactly schlank does. Ceramides serve [...] Related posts:Genetic Defect Inhibits Fruit Flies From Being Able To Store Fat — Are There Parallels To Humans?Gene regulates immune cells ability to harm the bodyGene Regulates Immune Cells Ability To Harm The Body

  • Polyphenols and polyunsaturated fatty acids boost the birth of new neurons

    Updated: 2009-11-25 15:22:27
    Story Summary: Polyunsaturated fatty acids can be found in blue fish and vegetables such as corn, soya beans, sunflowers and pumpkins. Previous studies had verified their effects on regulating cholesterol levels and hypertension, two risk factors commonly associated with heart disease and Alzheimers disease. During the development of the brain, stem cells generate different neural [...] Related posts:New Neurons Dont Heal / Science NewsUNC study pinpoints gene controlling number of brain cellsBlocked enzyme reverses schizophrenia-like symptoms

  • Tick Saliva: New Target for Lyme Disease Vaccine

    Updated: 2009-11-25 15:03:57
    Story Summary: In studies in mice, Howard Hughes Medical Institute researchers at Yale University produced an antiserum against a protein in tick saliva that significantly reduced the likelihood that mice could be infected with the tick-borne bacterium that causes Lyme disease. Lyme disease first manifests in humans as a rash that may pass unnoticed. This [...] Related posts:Yale Researchers Target Tick Saliva In Their Search For Lyme DiseaseYour pet should get a Lyme disease vaccination | Culpeper Star-ExponentRare deer tick virus identified as cause of death : Marthas Vineyard Times : June 4, 2009

  • DNA barcode for tropical trees

    Updated: 2009-11-25 11:53:33
    Story Summary: These fragments are then compared to a reference collection to identify their origin. A total of eight candidate barcodes were tested on over 200 tree species sampled at the CNRS Nouragues research station in French Guiana(2). More than 2,000 DNA sequences were thus generated for this project. Solving them would, among other things, [...] Related posts:Alnylam Joins GSK In Donating Intellectual Property To Patent Pool For Neglected Tropical DiseasesScientists unveil plant DNA barcodeBBC NEWS | Science & Environment | Barcode shows mosquito threats

  • New findings suggest strategy to help generate HIV-neutralising antibodies

    Updated: 2009-11-25 09:03:57
    Story Summary: Scientists know that an HIV-neutralising antibody called b12 binds to gp120, an HIV surface protein, at one of the few areas of the virus that does not mutate: the site where gp120 initially attaches to human immune cells. It was thought that exposing the human immune system to this site on gp120 would [...] Related posts:New findings suggest strategy to help generate HIV-neutralizing antibodiesGetting on the GABA receptor shuttle to treat anxiety disordersNovel genetic region identified for childhood asthma in Mexicans

  • Biologists discover bacterial defence mechanism against aggressive oxygen

    Updated: 2009-11-25 03:03:57
    Story Summary: This is the new finding of a team of biologists that includes Joris Messens of VIB, a life sciences research institute in Flanders, Belgium, connected to the Vrije Universiteit Brussel. The scientists made this discovery by modifying the DNA of the intestinal bacterium Escherichia coli. Proteins are the most important components of our [...] Related posts:Discovery By Biologists Of Bacterial Defense Mechanism Against Aggressive OxygenIndividual cells isolated from biological clock can keep daily time, but are unreliablePutting the squeeze on sperm DNA

  • The maize genome sequence is now complete

    Updated: 2009-11-25 02:17:33
    Story Summary: edu/video/v/Sequencing_the_Maize_GenomeThe first discoveries are published, along with the sequence itself, in the 20 November issue of Science. These accomplishments have been awarded the coveted cover spot in both journals. Additionally, the Science issue includes a limited number of a specially designed maize poster intended to serve biology readers with a Cliffs Notes(c) version [...] Related posts:Corn genome a maze of unusual diversityAmaizing: Corn genome decodedScientists complete genome sequence of cows – Science – Health & Science – The Times of India

  • Gene increases effectiveness of drugs used to fight cancer and allows reduction in dosage

    Updated: 2009-11-25 00:15:27
    Story Summary: Researchers at the University of Granadahave found a suicide gene, called gene E, which leads to the death of tumour cells derived from breast, lung and colon cancer, and prevents their growth. Advantages of gene therapyAs Ana Rosa Rama explains, chemotherapy, radiotherapy and surgery show at present limited results in advanced stages of [...] Related posts:Gene increases effectiveness of drugs used to fight cancer and allows reduction in dosageExpression Of Specific Genes Increases Lung Cancer RiskSelected Update: Anticancer drugs: microRNA suppresses liver cancer

  • Researchers aNOTCHa a victory in war on cancer

    Updated: 2009-11-24 21:29:33
    Story Summary: New molecule neutralizes key protein, once thought undruggableNovember 12, 2009Nicole DavisThe Broad Institute of Harvard and MITScientists have devised an innovative way to disarm a key protein considered to be undruggable, meaning that all previous efforts to develop a drug against it have failed. Their discovery, publishedin todays edition of the journal Nature, [...] Related posts:Researchers notch a victory toward new kind of cancer drugAileron collaborates study in Nature: Stapled peptides inhibit Notch1 transcription factorStabilized Helix Cracks Cancer Target

  • Technique finds gene regulatory sites without knowledge of regulators

    Updated: 2009-11-24 21:03:57
    Story Summary: The technique has been experimentally validated in both the mouse genome and the fruit fly genome. Our statistical approach is more widely applicable than other approaches, and is especially useful for investigating gene regulatory networks with relatively little prior characterisation, said Saurabh Sinha, a professor of computer science and an affiliate of the [...] Related posts:New UBC sequencing technique could boost pine beetle fight, improve cancer researchNew discoveries in the yeast Saccharomyces cerevisiaeTexas A and M researchers find new mechanism for circadian rhythm

  • Stem Cells Reduce Severe Angina Heart Pain

    Updated: 2009-11-24 05:39:15
    A person's own purified adult stem cells can reduce pain from a form of heart disease. CHICAGO --- The largest national stem cell study for heart disease showed the first evidence that transplanting a potent form of adult stem cells into the heart muscle of subjects with severe angina results in less pain and an improved ability to walk. The transplant subjects also experienced fewer deaths than those who didn't receive stem cells. In the 12-month Phase II, double-blind trial, subjects' own purified stem cells, called CD34+ cells, were injected into their hearts in an effort to spur the growth of small blood vessels that make up the microcirculation of the heart muscle. Researchers believe the loss of these blood...

  • Report Finds GM Crops Increase Pesticide Use and Resistant Weeds

    Updated: 2009-11-18 05:23:17
    (Beyond Pesticides, November 18, 2009) A report released yesterday and authored by Charles Benbrook, PhD, chief scientist at The Organic Center (TOC), finds that the rapid adoption by U.S. farmers of genetically modified corn, soybeans and cotton has promoted increased use of pesticides, an epidemic of herbicide-resistant weeds, and more chemical residues in foods. The [...]

  • Month in pictures - October 2009

    Updated: 2009-11-04 11:06:01
    Greenpeace's new Guide to Climate Politics shows just how badly the leaders of rich, industrialised nations are failing in their efforts to address climate change. In the last year developing nations have made real progress and put a series of offers on the table during the UN climate negotiations.

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